48 hours		3 months
Complete destruction of the glandular tissue due to coagulation necrosis lesion which reaches the capsula and the periprostatic fat.		The necrotic prostatic tissue is replaced by a fibrotic tissue (including the capsula).

Immediately after the HIFU treatment, biopsies evidenced a complete coagulation necrosis in the treated area (capsula and peri prostatic fat included). Later, after 3 months, fibrosis is replacing the necrotic tissue.